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Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer
Hepatocellular carcinoma (HCC) invariably exhibits inadequate O(2) (hypoxia) and nutrient supply. Hypoxia-inducible factor (HIF) mediates cascades of molecular events that enable cancer cells to adapt and propagate. Macropinocytosis is an endocytic process initiated by membrane ruffling, causing the...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854584/ https://www.ncbi.nlm.nih.gov/pubmed/35177645 http://dx.doi.org/10.1038/s41467-022-28618-9 |