Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer

Hepatocellular carcinoma (HCC) invariably exhibits inadequate O(2) (hypoxia) and nutrient supply. Hypoxia-inducible factor (HIF) mediates cascades of molecular events that enable cancer cells to adapt and propagate. Macropinocytosis is an endocytic process initiated by membrane ruffling, causing the...

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Detalles Bibliográficos
Autores principales: Zhang, Misty Shuo, Cui, Jane Di, Lee, Derek, Yuen, Vincent Wai-Hin, Chiu, David Kung-Chun, Goh, Chi Ching, Cheu, Jacinth Wing-Sum, Tse, Aki Pui-Wah, Bao, Macus Hao-Ran, Wong, Bowie Po Yee, Chen, Carrie Yiling, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854584/
https://www.ncbi.nlm.nih.gov/pubmed/35177645
http://dx.doi.org/10.1038/s41467-022-28618-9

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