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Amyloid-β(42) stimulated hippocampal lactate release is coupled to glutamate uptake
Since brain glucose hypometabolism is a feature of Alzheimer’s disease (AD) progression, lactate utilization as an energy source may become critical to maintaining central bioenergetics. We have previously shown that soluble amyloid-β (Aβ)(42) stimulates glutamate release through the α7 nicotinic ac...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854608/ https://www.ncbi.nlm.nih.gov/pubmed/35177691 http://dx.doi.org/10.1038/s41598-022-06637-2 |