Inhibition of HIF-1α-AQP4 axis ameliorates brain edema and neurological functional deficits in a rat controlled cortical injury (CCI) model

Traumatic brain injury (TBI) is an important cause of death in young adults and children. Till now, the treatment of TBI in the short- and long-term complications is still a challenge. Our previous evidence implied aquaporin 4 (AQP4) and hypoxia inducible factor-1α (HIF-1α) might be potential target...

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Detalles Bibliográficos
Autores principales: Xiong, Ao, Li, Junxia, Xiong, Renping, Xia, Yiming, Jiang, Xu, Cao, Fuyang, Lu, Hong, Xu, Jianzhong, Shan, Fabo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854620/
https://www.ncbi.nlm.nih.gov/pubmed/35177771
http://dx.doi.org/10.1038/s41598-022-06773-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854620/
https://www.ncbi.nlm.nih.gov/pubmed/35177771
http://dx.doi.org/10.1038/s41598-022-06773-9

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