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Ret kinase-mediated mechanical induction of colon stem cells by tumor growth pressure stimulates cancer progression in vivo

How mechanical stress actively impacts the physiology and pathophysiology of cells and tissues is little investigated in vivo. The colon is constantly submitted to multi-frequency spontaneous pulsatile mechanical waves, which highest frequency functions, of 2 s period, remain poorly understood. Here...

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Detalles Bibliográficos
Autores principales: Nguyen Ho-Bouldoires, Thanh Huong, Sollier, Kévin, Zamfirov, Laura, Broders-Bondon, Florence, Mitrossilis, Démosthène, Bermeo, Sebastian, Guerin, Coralie L., Chipont, Anna, Champenois, Gabriel, Leclère, Renaud, André, Nicolas, Ranno, Laurent, Michel, Aude, Ménager, Christine, Meseure, Didier, Demené, Charlie, Tanter, Mickael, Fernández-Sánchez, Maria Elena, Farge, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854631/
https://www.ncbi.nlm.nih.gov/pubmed/35177769
http://dx.doi.org/10.1038/s42003-022-03079-4