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Ret kinase-mediated mechanical induction of colon stem cells by tumor growth pressure stimulates cancer progression in vivo
How mechanical stress actively impacts the physiology and pathophysiology of cells and tissues is little investigated in vivo. The colon is constantly submitted to multi-frequency spontaneous pulsatile mechanical waves, which highest frequency functions, of 2 s period, remain poorly understood. Here...
Autores principales: | Nguyen Ho-Bouldoires, Thanh Huong, Sollier, Kévin, Zamfirov, Laura, Broders-Bondon, Florence, Mitrossilis, Démosthène, Bermeo, Sebastian, Guerin, Coralie L., Chipont, Anna, Champenois, Gabriel, Leclère, Renaud, André, Nicolas, Ranno, Laurent, Michel, Aude, Ménager, Christine, Meseure, Didier, Demené, Charlie, Tanter, Mickael, Fernández-Sánchez, Maria Elena, Farge, Emmanuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854631/ https://www.ncbi.nlm.nih.gov/pubmed/35177769 http://dx.doi.org/10.1038/s42003-022-03079-4 |
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