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The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development

How a single neuronal population diversifies into subtypes with distinct synaptic targets is a fundamental topic in neuroscience whose underlying mechanisms are unclear. Here, we show that the histone H3-lysine 27 demethylase Kdm6b regulates the diversification of motor neurons to distinct subtypes...

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Detalles Bibliográficos
Autores principales: Wang, Wenxian, Cho, Hyeyoung, Lee, Jae W., Lee, Soo-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854633/
https://www.ncbi.nlm.nih.gov/pubmed/35177643
http://dx.doi.org/10.1038/s41467-022-28636-7