Chemical reversible crosslinking enables measurement of RNA 3D distances and alternative conformations in cells

Three-dimensional (3D) structures dictate the functions of RNA molecules in a wide variety of biological processes. However, direct determination of RNA 3D structures in vivo is difficult due to their large sizes, conformational heterogeneity, and dynamics. Here we present a method, Spatial 2′-Hydro...

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Detalles Bibliográficos
Autores principales: Van Damme, Ryan, Li, Kongpan, Zhang, Minjie, Bai, Jianhui, Lee, Wilson H., Yesselman, Joseph D., Lu, Zhipeng, Velema, Willem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854666/
https://www.ncbi.nlm.nih.gov/pubmed/35177610
http://dx.doi.org/10.1038/s41467-022-28602-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854666/
https://www.ncbi.nlm.nih.gov/pubmed/35177610
http://dx.doi.org/10.1038/s41467-022-28602-3

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