Tumor stromal nicotinamide N-methyltransferase overexpression as a prognostic biomarker for poor clinical outcome in early-stage colorectal cancer

In a quest for prognostic biomarkers in early-stage colorectal cancer, we investigated NNMT (nicotinamide N-methyltransferase) in large cohorts of patients. Immunohistochemical examination of 679 patients illustrates that NNMT protein is predominantly expressed in the cancer stroma at varying levels...

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Detalles Bibliográficos
Autores principales: Ogawa, Makiko, Tanaka, Atsushi, Namba, Kei, Shia, Jinru, Wang, Julia Y., Roehrl, Michael H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854702/
https://www.ncbi.nlm.nih.gov/pubmed/35177765
http://dx.doi.org/10.1038/s41598-022-06772-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854702/
https://www.ncbi.nlm.nih.gov/pubmed/35177765
http://dx.doi.org/10.1038/s41598-022-06772-w

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