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Tumor stromal nicotinamide N-methyltransferase overexpression as a prognostic biomarker for poor clinical outcome in early-stage colorectal cancer
In a quest for prognostic biomarkers in early-stage colorectal cancer, we investigated NNMT (nicotinamide N-methyltransferase) in large cohorts of patients. Immunohistochemical examination of 679 patients illustrates that NNMT protein is predominantly expressed in the cancer stroma at varying levels...
Autores principales: | Ogawa, Makiko, Tanaka, Atsushi, Namba, Kei, Shia, Jinru, Wang, Julia Y., Roehrl, Michael H. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854702/ https://www.ncbi.nlm.nih.gov/pubmed/35177765 http://dx.doi.org/10.1038/s41598-022-06772-w |
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