A human tau seeded neuronal cell model recapitulates molecular responses associated with Alzheimer’s disease

Cellular models recapitulating features of tauopathies are useful tools to investigate the causes and consequences of tau aggregation and the identification of novel treatments. We seeded rat primary cortical neurons with tau isolated from Alzheimer’s disease brains to induce a time-dependent increa...

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Detalles Bibliográficos
Autores principales: Ficulle, Elena, Kananathan, Sarubini, Airey, David, Gharbi, Severine I., Humphryes-Kirilov, Neil, Scherschel, James, Dunbar, Charlotte, Eastwood, Brian J., Laing, Emma, Collier, David A., Bose, Suchira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854741/
https://www.ncbi.nlm.nih.gov/pubmed/35177665
http://dx.doi.org/10.1038/s41598-022-06411-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854741/
https://www.ncbi.nlm.nih.gov/pubmed/35177665
http://dx.doi.org/10.1038/s41598-022-06411-4

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