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The HVEM-BTLA Immune Checkpoint Restrains Murine Chronic Cholestatic Liver Injury by Regulating the Gut Microbiota

The herpes virus entry mediator (HVEM) is an immune checkpoint molecule regulating immune response, but its role in tissue repair remains unclear. Here, we reported that HVEM deficiency aggravated hepatobiliary damage and compromised liver repair after 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC)...

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Detalles Bibliográficos
Autores principales: Kou, Yanbo, Zheng, Xingping, Meng, Liyuan, Liu, Mengnan, Xu, Shihong, Jing, Qiyue, Zhang, Shenghan, Wang, Hanying, Han, Jinzhi, Liu, Zhuanzhuan, Wei, Yanxia, Wang, Yugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854854/
https://www.ncbi.nlm.nih.gov/pubmed/35185877
http://dx.doi.org/10.3389/fimmu.2022.773341