Trypanosoma cruzi Mitochondrial Peroxiredoxin Promotes Infectivity in Macrophages and Attenuates Nifurtimox Toxicity

Trypanosoma cruzi is the causative agent of Chagas disease which is currently treated by nifurtimox (NFX) and benznidazole (BZ). Nevertheless, the mechanism of action of NFX is not completely established. Herein, we show the protective effects of T. cruzi mitochondrial peroxiredoxin (MPX) in macroph...

Descripción completa

Detalles Bibliográficos
Autores principales: Specker, Gabriela, Estrada, Damián, Radi, Rafael, Piacenza, Lucía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855072/
https://www.ncbi.nlm.nih.gov/pubmed/35186785
http://dx.doi.org/10.3389/fcimb.2022.749476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855072/
https://www.ncbi.nlm.nih.gov/pubmed/35186785
http://dx.doi.org/10.3389/fcimb.2022.749476

Ejemplares similares