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DecOT: Bulk Deconvolution With Optimal Transport Loss Using a Single-Cell Reference
Tissues are constituted of heterogeneous cell types. Although single-cell RNA sequencing has paved the way to a deeper understanding of organismal cellular composition, the high cost and technical noise have prevented its wide application. As an alternative, computational deconvolution of bulk tissu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855157/ https://www.ncbi.nlm.nih.gov/pubmed/35186040 http://dx.doi.org/10.3389/fgene.2022.825896 |