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DecOT: Bulk Deconvolution With Optimal Transport Loss Using a Single-Cell Reference

Tissues are constituted of heterogeneous cell types. Although single-cell RNA sequencing has paved the way to a deeper understanding of organismal cellular composition, the high cost and technical noise have prevented its wide application. As an alternative, computational deconvolution of bulk tissu...

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Detalles Bibliográficos
Autores principales:	Liu, Gan, Liu, Xiuqin, Ma, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855157/ https://www.ncbi.nlm.nih.gov/pubmed/35186040 http://dx.doi.org/10.3389/fgene.2022.825896

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