CTCF-mediated chromatin looping provides a topological framework for the formation of phase-separated transcriptional condensates

CTCF is crucial to the organization of mammalian genomes into loop structures. According to recent studies, the transcription apparatus is compartmentalized and concentrated at super-enhancers to form phase-separated condensates and drive the expression of cell-identity genes. However, it remains un...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Ryanggeun, Kang, Moo-Koo, Kim, Yong-Jin, Yang, Bobae, Shim, Hwanyong, Kim, Sugyung, Kim, Kyungwoo, Yang, Chul Min, Min, Byeong-gyu, Jung, Woong-Jae, Lee, Eun-Chong, Joo, Jung-Sik, Park, Gunhee, Cho, Won-Ki, Kim, Hyoung-Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855298/
https://www.ncbi.nlm.nih.gov/pubmed/34931241
http://dx.doi.org/10.1093/nar/gkab1242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855298/
https://www.ncbi.nlm.nih.gov/pubmed/34931241
http://dx.doi.org/10.1093/nar/gkab1242

Ejemplares similares