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Nuclear poly(A) binding protein 1 (PABPN1) mediates zygotic genome activation-dependent maternal mRNA clearance during mouse early embryonic development

An embryo starts its life with maternal mRNA clearance, which is crucial for embryonic development. The elimination of maternal transcripts occurs by the joint action of two pathways: the maternally encoded mRNA decay pathway (M-decay) and the zygotic genome activation (ZGA)-dependent pathway (Z-dec...

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Detalles Bibliográficos
Autores principales: Zhao, Long-Wen, Zhu, Ye-Zhang, Wu, Yun-Wen, Pi, Shuai-Bo, Shen, Li, Fan, Heng-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855302/
https://www.ncbi.nlm.nih.gov/pubmed/34904664
http://dx.doi.org/10.1093/nar/gkab1213