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Molecular Basis of Small-Molecule Binding to α-Synuclein
[Image: see text] Intrinsically disordered proteins (IDPs) are implicated in many human diseases. They have generally not been amenable to conventional structure-based drug design, however, because their intrinsic conformational variability has precluded an atomic-level understanding of their bindin...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855421/ https://www.ncbi.nlm.nih.gov/pubmed/35130691 http://dx.doi.org/10.1021/jacs.1c07591 |