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Classifying liganded states in heterogeneous single-particle cryo-EM datasets

A powerful aspect of single-particle cryogenic electron microscopy is its ability to determine high-resolution structures from samples containing heterogeneous mixtures of the same macromolecule in different conformational or compositional states. Beyond determining structures at higher resolutions,...

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Detalles Bibliográficos
Autores principales: Arnold, William R, Asarnow, Daniel, Cheng, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855519/
https://www.ncbi.nlm.nih.gov/pubmed/34718671
http://dx.doi.org/10.1093/jmicro/dfab044