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Functional interaction between S100A1 and MDM2 may modulate p53 signaling in normal and malignant endometrial cells

BACKGROUND: S100A1 expression is deregulated in a variety of human malignancies, but its role in normal and malignant endometrial cells is unclear. METHODS: We used endometrial carcinoma (Em Ca) cell lines to evaluate the physical and functional interaction of S100A1 with p53 and its negative regula...

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Detalles Bibliográficos
Autores principales: Nakagawa, Mayu, Higuchi, Shyoma, Hashimura, Miki, Oguri, Yasuko, Matsumoto, Toshihide, Yokoi, Ako, Ishibashi, Yu, Ito, Takashi, Saegusa, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855586/
https://www.ncbi.nlm.nih.gov/pubmed/35177036
http://dx.doi.org/10.1186/s12885-022-09249-1