Cargando…
Competition between type I activin and BMP receptors for binding to ACVR2A regulates signaling to distinct Smad pathways
BACKGROUND: Activins and bone morphogenetic proteins (BMPs) play critical, sometimes opposing roles, in multiple physiological and pathological processes and diseases. They signal to distinct Smad branches; activins signal mainly to Smad2/3, while BMPs activate mainly Smad1/5/8. This gives rise to t...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855587/ https://www.ncbi.nlm.nih.gov/pubmed/35177083 http://dx.doi.org/10.1186/s12915-022-01252-z |