Choroid plexus-selective inactivation of adenosine A(2A) receptors protects against T cell infiltration and experimental autoimmune encephalomyelitis

BACKGROUND: Multiple sclerosis (MS) is one of the most common autoimmune disorders characterized by the infiltration of immune cells into the brain and demyelination. The unwanted immunosuppressive side effect of therapeutically successful natalizumab led us to focus on the choroid plexus (CP), a ke...

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Detalles Bibliográficos
Autores principales: Zheng, Wu, Feng, Yijia, Zeng, Zhenhai, Ye, Mengqian, Wang, Mengru, Liu, Xin, Tang, Ping, Shang, Huiping, Sun, Xiaoting, Lin, Xiangxiang, Wang, Muran, Li, Zhengzheng, Weng, Yiyun, Guo, Wei, Vakal, Sergii, Chen, Jiang-fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855604/
https://www.ncbi.nlm.nih.gov/pubmed/35180864
http://dx.doi.org/10.1186/s12974-022-02415-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855604/
https://www.ncbi.nlm.nih.gov/pubmed/35180864
http://dx.doi.org/10.1186/s12974-022-02415-z

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