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Choroid plexus-selective inactivation of adenosine A(2A) receptors protects against T cell infiltration and experimental autoimmune encephalomyelitis
BACKGROUND: Multiple sclerosis (MS) is one of the most common autoimmune disorders characterized by the infiltration of immune cells into the brain and demyelination. The unwanted immunosuppressive side effect of therapeutically successful natalizumab led us to focus on the choroid plexus (CP), a ke...
Autores principales: | Zheng, Wu, Feng, Yijia, Zeng, Zhenhai, Ye, Mengqian, Wang, Mengru, Liu, Xin, Tang, Ping, Shang, Huiping, Sun, Xiaoting, Lin, Xiangxiang, Wang, Muran, Li, Zhengzheng, Weng, Yiyun, Guo, Wei, Vakal, Sergii, Chen, Jiang-fan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855604/ https://www.ncbi.nlm.nih.gov/pubmed/35180864 http://dx.doi.org/10.1186/s12974-022-02415-z |
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