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Nasal delivery of broadly neutralizing antibodies protects mice from lethal challenge with SARS-CoV-2 delta and omicron variants

Multiple new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have constantly emerged, as the delta and omicron variants, which have developed resistance to currently gained neutralizing antibodies. This highlights a critical need to discover new therapeutic agents to overcom...

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Detalles Bibliográficos
Autores principales: Lu, Jia, Yin, Qiangling, Pei, Rongjuan, Zhang, Qiu, Qu, Yuanyuan, Pan, Yongbing, Sun, Lina, Gao, Ding, Liang, Cuiqin, Yang, Jingwen, Wu, Wei, Li, Jiandong, Cui, Zongqiang, Wang, Zejun, Li, Xinguo, Li, Dexin, Wang, Shiwen, Duan, Kai, Guan, Wuxiang, Liang, Mifang, Yang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855614/
https://www.ncbi.nlm.nih.gov/pubmed/35527227
http://dx.doi.org/10.1016/j.virs.2022.02.005