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The glucose lowering effects of CL 316,243 dissipate with repeated use and are rescued bycilostamide

Repeated activation of the beta 3 adrenergic receptor (β3AR) with the agonist CL 316,243 (CL) results in remodeling of white adipose tissue (WAT) characterized by increased mitochondrial enzymes and expression of uncoupling protein 1 (UCP1). β3AR activation also has profound acute metabolic effects...

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Detalles Bibliográficos
Autores principales: Medak, Kyle D., McKie, Greg L., Shamshoum, Hesham, Seguin, Ian, Wright, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855634/
https://www.ncbi.nlm.nih.gov/pubmed/35179321
http://dx.doi.org/10.14814/phy2.15187