7,8-Dihydroxyflavone protects neurons against oxygen-glucose deprivation induced apoptosis and activates the TrkB/Akt pathway

BACKGROUND: 7,8-dihydroxyflavone (7,8-DHF), a selective agonist of tropomyosin related kinase receptor B (TrkB), is known to exert protective effects in neurodegenerative diseases. However, the role of 7,8-DHF in TrkB signaling after ischemic stroke has remained elusive. METHODS: In the vitro model...

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Detalles Bibliográficos
Autores principales: Zhou, Qinxiang, Tang, Hao, Bai, Dingqun, Kong, Yuhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855723/
https://www.ncbi.nlm.nih.gov/pubmed/35186478
http://dx.doi.org/10.7717/peerj.12886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855723/
https://www.ncbi.nlm.nih.gov/pubmed/35186478
http://dx.doi.org/10.7717/peerj.12886

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