DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3

Discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase activated by collagen, contributes to chronic kidney disease. However, its role in acute kidney injury and subsequent development of kidney fibrosis is not clear. Thus, we performed a model of severe ischemia/reperfusion-induced acute ki...

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Detalles Bibliográficos
Autores principales: Borza, Corina M., Bolas, Gema, Bock, Fabian, Zhang, Xiuqi, Akabogu, Favour C., Zhang, Ming-Zhi, de Caestecker, Mark, Yang, Min, Yang, Haichun, Lee, Ethan, Gewin, Leslie, Fogo, Agnes B., McDonald, W. Hayes, Zent, Roy, Pozzi, Ambra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855801/
https://www.ncbi.nlm.nih.gov/pubmed/34941574
http://dx.doi.org/10.1172/jci.insight.150887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855801/
https://www.ncbi.nlm.nih.gov/pubmed/34941574
http://dx.doi.org/10.1172/jci.insight.150887

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