Tumor-infiltrating exhausted CD8(+) T cells dictate reduced survival in premenopausal estrogen receptor–positive breast cancer

CD8(+) tumor-infiltrating lymphocytes (TILs) are associated with improved survival in triple-negative breast cancer (TNBC) yet have no association with survival in estrogen receptor–positive (ER(+)) BC. The basis for these contrasting findings remains elusive. We identified subsets of BC tumors infi...

Descripción completa

Detalles Bibliográficos
Autores principales: Egelston, Colt A., Guo, Weihua, Tan, Jiayi, Avalos, Christian, Simons, Diana L., Lim, Min Hui, Huang, Yinghui J., Nelson, Michael S., Chowdhury, Arnab, Schmolze, Daniel B., Yim, John H., Kruper, Laura, Melstrom, Laleh, Margolin, Kim, Mortimer, Joanne E., Yuan, Yuan, Waisman, James R., Lee, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855819/
https://www.ncbi.nlm.nih.gov/pubmed/35132960
http://dx.doi.org/10.1172/jci.insight.153963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855819/
https://www.ncbi.nlm.nih.gov/pubmed/35132960
http://dx.doi.org/10.1172/jci.insight.153963

Ejemplares similares