NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice

Immune cells express an array of inhibitory checkpoint receptors that are upregulated upon activation and limit tissue damage associated with excessive response to pathogens or allergens. Mouse leukocyte immunoglobulin like receptor B4 (LILRB4), also known as glycoprotein 49B (gp49B), is an inhibito...

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Detalles Bibliográficos
Autores principales: Lee, Ha-Na, Manangeeswaran, Mohanraj, Lewkowicz, Aaron P., Engel, Kaliroi, Chowdhury, Monica, Garige, Mamatha, Eckhaus, Michael A., Sourbier, Carole, Ireland, Derek D.C., Verthelyi, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855830/
https://www.ncbi.nlm.nih.gov/pubmed/35132958
http://dx.doi.org/10.1172/jci.insight.151420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855830/
https://www.ncbi.nlm.nih.gov/pubmed/35132958
http://dx.doi.org/10.1172/jci.insight.151420

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