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NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice
Immune cells express an array of inhibitory checkpoint receptors that are upregulated upon activation and limit tissue damage associated with excessive response to pathogens or allergens. Mouse leukocyte immunoglobulin like receptor B4 (LILRB4), also known as glycoprotein 49B (gp49B), is an inhibito...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855830/ https://www.ncbi.nlm.nih.gov/pubmed/35132958 http://dx.doi.org/10.1172/jci.insight.151420 |