Impairing RAGE signaling promotes survival and limits disease pathogenesis following SARS-CoV-2 infection in mice

Cellular and molecular mechanisms driving morbidity following SARS-CoV-2 infection have not been well defined. The receptor for advanced glycation end products (RAGE) is a central mediator of tissue injury and contributes to SARS-CoV-2 disease pathogenesis. In this study, we temporally delineated ke...

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Detalles Bibliográficos
Autores principales: Jessop, Forrest, Schwarz, Benjamin, Scott, Dana, Roberts, Lydia M., Bohrnsen, Eric, Hoidal, John R., Bosio, Catharine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855831/
https://www.ncbi.nlm.nih.gov/pubmed/35076028
http://dx.doi.org/10.1172/jci.insight.155896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855831/
https://www.ncbi.nlm.nih.gov/pubmed/35076028
http://dx.doi.org/10.1172/jci.insight.155896

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