Liquid biopsy reveals collateral tissue damage in cancer

Cancer inflicts damage to surrounding normal tissues, which can culminate in fatal organ failure. Here, we demonstrate that cell death in organs affected by cancer can be detected by tissue-specific methylation patterns of circulating cell-free DNA (cfDNA). We detected elevated levels of hepatocyte-...

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Detalles Bibliográficos
Autores principales: Lubotzky, Asael, Zemmour, Hai, Neiman, Daniel, Gotkine, Marc, Loyfer, Netanel, Piyanzin, Sheina, Ochana, Bracha-Lea, Lehmann-Werman, Roni, Cohen, Daniel, Moss, Joshua, Magenheim, Judith, Loftus, Maureen F., Brais, Lauren, Ng, Kimmie, Mostoslavsky, Raul, Wolpin, Brian M., Zick, Aviad, Maoz, Myriam, Grinshpun, Albert, Kustanovich, Anatoli, Makranz, Chen, Cohen, Jonathan E., Peretz, Tamar, Hubert, Ayala, Temper, Mark, Salah, Azzam, Avniel-Polak, Shani, Grozinsky-Glasberg, Simona, Spalding, Kirsty L., Rokach, Ariel, Kaplan, Tommy, Glaser, Benjamin, Shemer, Ruth, Dor, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855834/
https://www.ncbi.nlm.nih.gov/pubmed/35076021
http://dx.doi.org/10.1172/jci.insight.153559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855834/
https://www.ncbi.nlm.nih.gov/pubmed/35076021
http://dx.doi.org/10.1172/jci.insight.153559

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