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Dissecting the mechanism of cytokine release induced by T-cell engagers highlights the contribution of neutrophils

T cell engagers represent a novel promising class of cancer-immunotherapies redirecting T cells to tumor cells and have some promising outcomes in the clinic. These molecules can be associated with a mode-of-action related risk of cytokine release syndrome (CRS) in patients. CRS is characterized by...

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Detalles Bibliográficos
Autores principales: Leclercq, Gabrielle, Servera, Llucia Alberti, Danilin, Sabrina, Challier, John, Steinhoff, Nathalie, Bossen, Claudia, Odermatt, Alex, Nicolini, Valeria, Umaña, Pablo, Klein, Christian, Bacac, Marina, Giusti, Anna-Maria, Schneider, Anneliese, Haegel, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855852/
https://www.ncbi.nlm.nih.gov/pubmed/35186442
http://dx.doi.org/10.1080/2162402X.2022.2039432