HIV-1 provirus transcription and translation in macrophages differs from pre-integrated cDNA complexes and requires E2F transcriptional programs

HIV-1 cDNA pre-integration complexes persist for weeks in macrophages and remain transcriptionally active. While previous work has focused on the transcription of HIV-1 genes; our understanding of the cellular milieu that accompanies viral production is incomplete. We have used an in vitro system to...

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Detalles Bibliográficos
Autores principales: Lim, Albebson L., Moos, Philip, Pond, Christopher D., Larson, Erica C., Martins, Laura J., Szaniawski, Matthew A., Planelles, Vicente, Barrows, Louis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855869/
https://www.ncbi.nlm.nih.gov/pubmed/35166645
http://dx.doi.org/10.1080/21505594.2022.2031583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855869/
https://www.ncbi.nlm.nih.gov/pubmed/35166645
http://dx.doi.org/10.1080/21505594.2022.2031583

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