Proteome analysis of NRF2 inhibition in melanoma reveals CD44 up‐regulation and increased apoptosis resistance upon vemurafenib treatment

Malignant melanoma is the deadliest form of skin cancer and NRF2 has been proposed as a main regulator of tumor cell malignancy. Still the mechanisms how NRF2 is contributing to melanoma progression are incompletely understood. Here we analyzed the effects of either NRF2 induction or depletion, and...

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Detalles Bibliográficos
Autores principales: Weitzenböck, Hans Peter, Gschwendtner, Anna, Wiesner, Christoph, Depke, Maren, Schmidt, Frank, Trautinger, Franz, Hengstschläger, Markus, Hundsberger, Harald, Mikula, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855890/
https://www.ncbi.nlm.nih.gov/pubmed/34951143
http://dx.doi.org/10.1002/cam4.4506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855890/
https://www.ncbi.nlm.nih.gov/pubmed/34951143
http://dx.doi.org/10.1002/cam4.4506

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