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Heterogeneity among tumors with acquired resistance to EGFR tyrosine kinase inhibitors harboring EGFR‐T790M mutation in non‐small cell lung cancer cells

EGFR‐T790M mutation is a major mechanism underlying acquired resistance to first‐ and second‐generation EGFR tyrosine kinase inhibitors (EGFR‐TKIs) in lung cancer with mutated EGFR. However, differences in the biological characteristics of T790M tumors based on treatment regimens with each generatio...

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Detalles Bibliográficos
Autores principales: Katayama, Yuki, Yamada, Tadaaki, Tokuda, Shinsaku, Okura, Naoko, Nishioka, Naoya, Morimoto, Kenji, Tanimura, Keiko, Morimoto, Yoshie, Iwasaku, Masahiro, Horinaka, Mano, Sakai, Toshiyuki, Kita, Kenji, Yano, Seiji, Takayama, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855901/
https://www.ncbi.nlm.nih.gov/pubmed/35029047
http://dx.doi.org/10.1002/cam4.4504