Co-Delivery of p53 Restored and E7 Targeted Nucleic Acids by Poly (Beta-Amino Ester) Complex Nanoparticles for the Treatment of HPV Related Cervical Lesions

The p53 gene has the highest mutation frequency in tumors, and its inactivation can lead to malignant transformation, such as cell cycle arrest and apoptotic inhibition. Persistent high-risk human papillomavirus (HR-HPV) infection is the leading cause of cervical cancer. P53 was inactivated by HPV o...

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Detalles Bibliográficos
Autores principales: Xiong, Jinfeng, Li, Guannan, Mei, Xinyu, Ding, Jiahui, Shen, Hui, Zhu, Da, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855959/
https://www.ncbi.nlm.nih.gov/pubmed/35185576
http://dx.doi.org/10.3389/fphar.2022.826771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855959/
https://www.ncbi.nlm.nih.gov/pubmed/35185576
http://dx.doi.org/10.3389/fphar.2022.826771

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