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Identification of rare post-mitotic cell states induced by injury and required for whole-body regeneration in Schmidtea mediterranea

Regeneration requires coordination of stem cells, their progeny, and distant differentiated tissues. Here, we present a comprehensive atlas of whole-body regeneration in Schmidtea mediterranea and identify wound-induced cell states. Analysis of 299,998 single-cell transcriptomes captured from regene...

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Detalles Bibliográficos
Autores principales: Benham-Pyle, Blair W., Brewster, Carolyn E., Kent, Aubrey M., Mann, Frederick G., Chen, Shiyuan, Scott, Allison R., Box, Andrew C., Sánchez Alvarado, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855990/
https://www.ncbi.nlm.nih.gov/pubmed/34475533
http://dx.doi.org/10.1038/s41556-021-00734-6