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Potential test-negative design study bias in outbreak settings: application to Ebola vaccination in Democratic Republic of Congo

BACKGROUND: Infectious disease outbreaks present unique challenges to study designs for vaccine evaluation. Test-negative design (TND) studies have previously been used to estimate vaccine effectiveness and have been proposed for Ebola virus disease (EVD) vaccines. However, there are key differences...

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Detalles Bibliográficos
Autores principales: Pearson, Carl A B, Edmunds, W John, Hladish, Thomas J, Eggo, Rosalind M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855996/
https://www.ncbi.nlm.nih.gov/pubmed/34458913
http://dx.doi.org/10.1093/ije/dyab172