Hyaluronic acid-modified redox-sensitive hybrid nanocomplex loading with siRNA for non-small-cell lung carcinoma therapy

A novel hyaluronic acid (HA)-modified hybrid nanocomplex HA-SeSe-COOH/siR-93C@PAMAM, which could efficiently deliver siRNA into tumor cells via a redox-mediated intracellular disassembly, was constructed for enhanced antitumor efficacy. Thereinto, siR-93C (siRNA) and positive PAMAM were firstly mixe...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Daoyuan, Zhang, Peng, Li, Minghui, Li, Congcong, Lu, Xiaoyan, Sun, Yiying, Sun, Kaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856077/
https://www.ncbi.nlm.nih.gov/pubmed/35156491
http://dx.doi.org/10.1080/10717544.2022.2032874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856077/
https://www.ncbi.nlm.nih.gov/pubmed/35156491
http://dx.doi.org/10.1080/10717544.2022.2032874

Ejemplares similares