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Hyaluronic acid-modified redox-sensitive hybrid nanocomplex loading with siRNA for non-small-cell lung carcinoma therapy

A novel hyaluronic acid (HA)-modified hybrid nanocomplex HA-SeSe-COOH/siR-93C@PAMAM, which could efficiently deliver siRNA into tumor cells via a redox-mediated intracellular disassembly, was constructed for enhanced antitumor efficacy. Thereinto, siR-93C (siRNA) and positive PAMAM were firstly mixe...

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Detalles Bibliográficos
Autores principales:	Chen, Daoyuan, Zhang, Peng, Li, Minghui, Li, Congcong, Lu, Xiaoyan, Sun, Yiying, Sun, Kaoxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856077/ https://www.ncbi.nlm.nih.gov/pubmed/35156491 http://dx.doi.org/10.1080/10717544.2022.2032874

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