Comparative chemical and biological hydrolytic stability of homologous esters and isosteres

Esters are one of the major functional groups present in the structures of prodrugs and bioactive compounds. Their presence is often associated with hydrolytic lability. In this paper, we describe a comparative chemical and biological stability of homologous esters and isosteres in base media as wel...

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Detalles Bibliográficos
Autores principales: de Souza, Hygor M. R., Guedes, Jéssica S., Freitas, Rosana H. C. N., Gelves, Luis G. V., Fokoue, Harold H., Sant’Anna, Carlos Mauricio R., Barreiro, Eliezer J., Lima, Lidia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856110/
https://www.ncbi.nlm.nih.gov/pubmed/35156494
http://dx.doi.org/10.1080/14756366.2022.2027933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856110/
https://www.ncbi.nlm.nih.gov/pubmed/35156494
http://dx.doi.org/10.1080/14756366.2022.2027933

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