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A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy

Many SARS-CoV-2 variants have mutations at key sites targeted by antibodies. However, it is unknown if antibodies elicited by infection with these variants target the same or different regions of the viral spike as antibodies elicited by earlier viral isolates. Here we compare the specificities of p...

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Detalles Bibliográficos
Autores principales: Greaney, Allison J., Starr, Tyler N., Eguia, Rachel T., Loes, Andrea N., Khan, Khadija, Karim, Farina, Cele, Sandile, Bowen, John E., Logue, Jennifer K., Corti, Davide, Veesler, David, Chu, Helen Y., Sigal, Alex, Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856557/
https://www.ncbi.nlm.nih.gov/pubmed/35134084
http://dx.doi.org/10.1371/journal.ppat.1010248