Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α

Exogenous glucocorticoids interact with the circadian clock, but little attention is paid to the timing of intake. We recently found that intermittent once-weekly prednisone improved nutrient oxidation in dystrophic muscle. Here, we investigated whether dosage time affected prednisone effects on mus...

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Detalles Bibliográficos
Autores principales: Quattrocelli, Mattia, Wintzinger, Michelle, Miz, Karen, Levine, Daniel C., Peek, Clara Bien, Bass, Joseph, McNally, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856622/
https://www.ncbi.nlm.nih.gov/pubmed/35179955
http://dx.doi.org/10.1126/sciadv.abm1189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856622/
https://www.ncbi.nlm.nih.gov/pubmed/35179955
http://dx.doi.org/10.1126/sciadv.abm1189

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