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Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α
Exogenous glucocorticoids interact with the circadian clock, but little attention is paid to the timing of intake. We recently found that intermittent once-weekly prednisone improved nutrient oxidation in dystrophic muscle. Here, we investigated whether dosage time affected prednisone effects on mus...
Autores principales: | Quattrocelli, Mattia, Wintzinger, Michelle, Miz, Karen, Levine, Daniel C., Peek, Clara Bien, Bass, Joseph, McNally, Elizabeth M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856622/ https://www.ncbi.nlm.nih.gov/pubmed/35179955 http://dx.doi.org/10.1126/sciadv.abm1189 |
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