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The NDNF-like factor Nord is a Hedgehog-induced extracellular BMP modulator that regulates Drosophila wing patterning and growth

Hedgehog (Hh) and Bone Morphogenetic Proteins (BMPs) pattern the developing Drosophila wing by functioning as short- and long-range morphogens, respectively. Here, we show that a previously unknown Hh-dependent mechanism fine-tunes the activity of BMPs. Through genome-wide expression profiling of th...

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Detalles Bibliográficos
Autores principales: Yang, Shu, Wu, Xuefeng, Daoutidou, Euphrosyne I, Zhang, Ya, Shimell, MaryJane, Chuang, Kun-Han, Peterson, Aidan J, O'Connor, Michael B, Zheng, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856659/
https://www.ncbi.nlm.nih.gov/pubmed/35037619
http://dx.doi.org/10.7554/eLife.73357