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Chronic hM4Di-DREADD-Mediated Chemogenetic Inhibition of Forebrain Excitatory Neurons in Postnatal or Juvenile Life Does Not Alter Adult Mood-Related Behavior

G-protein-coupled receptors (GPCRs) coupled to G(i) signaling, in particular downstream of monoaminergic neurotransmission, are posited to play a key role during developmental epochs (postnatal and juvenile) in shaping the emergence of adult anxiodepressive behaviors and sensorimotor gating. To addr...

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Detalles Bibliográficos
Autores principales: Tiwari, Praachi, Kapri, Darshana, Pradhan, Amartya, Balakrishnan, Angarika, Chaudhari, Pratik R., Vaidya, Vidita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856708/
https://www.ncbi.nlm.nih.gov/pubmed/35115382
http://dx.doi.org/10.1523/ENEURO.0381-21.2021