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Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir

The COVID-19 pandemic continues to be a public health threat. Multiple mutations in the spike protein of emerging variants of SARS-CoV-2 appear to impact on the effectiveness of available vaccines. Specific antiviral agents are keenly anticipated but their efficacy may also be compromised in emergin...

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Detalles Bibliográficos
Autores principales: Ullrich, Sven, Ekanayake, Kasuni B., Otting, Gottfried, Nitsche, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856729/
https://www.ncbi.nlm.nih.gov/pubmed/35182772
http://dx.doi.org/10.1016/j.bmcl.2022.128629