The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner

The NKCC1 ion transporter contributes to the pathophysiology of common neurological disorders, but its function in microglia, the main inflammatory cells of the brain, has remained unclear to date. Therefore, we generated a novel transgenic mouse line in which microglial NKCC1 was deleted. We show t...

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Detalles Bibliográficos
Autores principales: Tóth, Krisztina, Lénárt, Nikolett, Berki, Péter, Fekete, Rebeka, Szabadits, Eszter, Pósfai, Balázs, Cserép, Csaba, Alatshan, Ahmad, Benkő, Szilvia, Kiss, Dániel, Hübner, Christian A., Gulyás, Attila, Kaila, Kai, Környei, Zsuzsanna, Dénes, Ádám
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856735/
https://www.ncbi.nlm.nih.gov/pubmed/35085235
http://dx.doi.org/10.1371/journal.pbio.3001526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856735/
https://www.ncbi.nlm.nih.gov/pubmed/35085235
http://dx.doi.org/10.1371/journal.pbio.3001526

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