Sjögren-Larsson syndrome: A biochemical rationale for using aldehyde-reactive therapeutic agents

Sjögren-Larsson syndrome (SLS) is a neurocutaneous disease caused by mutations in ALDH3A2 that result in deficient fatty aldehyde dehydrogenase (FALDH) activity and impaired fatty aldehyde and fatty alcohol oxidation. The pathogenesis of SLS is thought to involve accumulation of long-chain fatty ald...

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Detalles Bibliográficos
Autores principales: Rizzo, William B., S'aulis, Dana, Dorwart, Elizabeth, Bailey, Zachary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856915/
https://www.ncbi.nlm.nih.gov/pubmed/35242571
http://dx.doi.org/10.1016/j.ymgmr.2021.100839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856915/
https://www.ncbi.nlm.nih.gov/pubmed/35242571
http://dx.doi.org/10.1016/j.ymgmr.2021.100839

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